货号 | 1763/1 |
供应商 | Tocris |
生物活性 | Endogenous peptide fragment that is a selective agonist for the sensory neuron specific receptor (EC50 values are 28 and 14 nM for SNSR3 and SNSR4 respectively); first isolated from bovine adrenal medulla. Unlike BAM 22P (Cat. No. 1650), does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 1971.22 |
分子式 | C91H127N25O23S |
可溶性/溶解性 | Soluble to 1 mg/ml in water |
CAS号 | 412961-36-5 |
序列号 | VGRPEWWMDYQKRYG |
参考文献 | Chen and Ikeda (2004) Modulation of ion channels and synaptic transmission by a human sensory neuron-specific G-protein-coupled receptor, SNSR4/mrgX1, heterologously expressed in cultured rat neurons. J.Neurosci. 24 5044. PMID: 15163697. Lemboet al (2002) Proenkephalin A gene products activate a new family of sensory neuron-specific GPCRs. Nat.Neurosci. 5 201. PMID: 11850634. Simonin and Kieffer (2002) Two faces for an opioid peptide - and more receptors for pain research. Nat.Neurosci. 5 185. PMID: 11865303. |