1.Graff, J.R.,McNulty, A.M.,Hanna, K.R., et al. The protein kinase Cβ-selective inhibitor, enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. Cancer Research 65(16), 7462-7469 (2005). 2.Querfeld, C.,Rizvi, M.A.,Kuzel, T.M., et al. The selective protein kinase C β inhibitor enzastaurin induces apoptosis in cutaneous T-cell lymphoma cell lines through the AKT pathway. Journal of Investigative Dermatology 126(7), 1641-1647 (2006). 3.Herbst, R.S.,Oh, Y.,Wagle, A., et al. Enzastaurin, a protein kinase Cβ-selective inhibitor, and its potential application as an anticancer agent in lung cancer. Clinical Cancer Research 13(15.2), s4641-s4646 (2007).
|