SYK Inhibitor, R406
货号:
9682-25 基本售价:
4812.5 元 规格:
25mg
产品信息
概述货号 | 9682-25 |
描述 | R406 is a potent SYK (Spleen Tyrosine Kinase) inhibitor (IC₅₀ = 41 nM). R406 strongly inhibits SYK but not Lyn, and displays 5-fold less potency towards FLT3. R406 induces apoptosis in diffuse large B-cell lymphoma cell lines. It blocks B cell receptor signaling through inhibition of SYK autophosphorylation of Y525/Y526 and SYK-dependent phosphorylation of the B-cell linker protein. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | Off-white solid |