货号 | 9674-25 |
描述 | L-189 is a DNA ligase I, III and IV inhibitor (IC₅₀ values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki= 5 μM for DNA ligase I). L-189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L-189 specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. |
供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | White solid |