货号 | 2609-25 |
描述 | XL019 is a potent, highly selective and reversible JAK2 inhibitor (IC₅₀ = 2.2 nM). Inhibits JAK1 (IC₅₀ = 134.3 nM), JAK3 (IC50 = 214.2 nM) and TYK2 (IC₅₀ = 348.3 nM) at higher concentrations. XL019 displays significant dose-dependent pharmacodynamic and antitumor effect in a mouse xenograft model. |
供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20 ̊C |
外观 | Light yellow to light brown solid |