| 货号 | 2308/10 |
| 别名 | N-[(2E)-5-Amino-5-methyl-1-oxo-2-he |
| 供应商 | Tocris |
| 生物活性 | Potent, orally active ghrelin receptor (GHS-R1a) agonist (Ki = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC50 value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 586.73 |
| 分子式 | C32H40N4O3.紺4H4O4 |
| 可溶性/溶解性 | Soluble to 10 mM in water with gentle warming and to 100 mM in DMSO |
| CAS号 | 193079-69-5 |
| 参考文献 | Holmet al (2004) Adipogenic and orexigenic effects of the ghrelin-receptor ligand tabimorelin are diminished in leptin-signalling-deficient ZDF rats. Eur.J.Pharmacol. 150893. Hansenet al (1999) Pharmacological characterisation of a new oral GH secretagogue, NN703. Eur.J.Endocrinol. 141 180. PMID: 10427162. |