| 货号 | 4978/10 |
| 别名 | N-(Cyclopropylmethyl)-4-[[4-(3,4-di |
| 供应商 | Tocris |
| 生物活性 | Enhances survival of human embryonic stem cells (hESCs) following enzymatic dissociation. Thought to enhance cell-ECM adhesion and activate integrin signaling. Increases adhesion of hESCs to matrigel- and laminin-coated plates, but not to gelatin-coated plates. Also podocyte-protective agent and prevents LPS-induced proteinuria in mice. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >98 % |
| 计算分子量 | 451.54 |
| 分子式 | C23H25N5O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Leeet al (2015) A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. J.Am.Soc.Nephrol 26 2741. PMID: 25858967. Xuet al (2010) Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc.Natl.Acad.Sci.USA 107 8129. PMID: 20406903. |