| 货号 | 1600/2 |
| 供应商 | Tocris |
| 生物活性 | Inhibitor peptide that selectively disrupts binding of the AMPA receptor subunit GluR2 (at the C-terminal PDZ site) to protein interacting with C kinase (PICK1). Does not affect binding of GluR2 to GRIP or ABP and does not increase AMPA current amplitude or affect long term depression (LTD). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1268.47 |
| 分子式 | C60H93N13O17 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| 序列号 | YNVYGIEAVKI |
| 参考文献 | Hanleyet al (2002) NSF ATPase and α-/β-SNAPs disassemble the AMPA receptor-PICK1 complex. Neuron 34 53. PMID: 11931741. Kimet al (2001) Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression. Proc.Natl.Acad.Sci.U.S.A. 98 11725. PMID: 11573007. Dawet al (2000) PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron 28 873. PMID: 11163273. Liet al (1999) AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses. Nat.Neurosci. 2 972. PMID: 10526335. |