| 货号 | 4912/100U |
| 供应商 | Tocris |
| 生物活性 | TRPC1 and TRPC6 blocker. Also blocks stretch-activated cation channels in astrocytes, cardiac cells, and smooth and skeletal muscle cells. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4095.86 |
| 分子式 | C185H273N49O |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| 序列号 | GCLEFWWKCNPNDDKCCRPKLKCSKLFKLC (Modifications: Disulfide bridge: 2-17,9-23,16-30) (Modifications |
| 参考文献 | Bowmanet al (2007) Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology. Toxicon. 49 249. PMID: 17157345. Drewet al (2007) High-threshold mechanosensitive ion channels blocked by a novel conopeptide mediate pressure-evoked pain. PLoS One 2 e515. PMID: 17565368. Suchynaet al (2000) Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels. J.Gen.Physiol. 115 583. PMID: 10779316. |