| 货号 | 1775/1 |
| 供应商 | Tocris |
| 生物活性 | Cell-permeable version of dynamin inhibitory peptide (Cat. No. 1774), an inhibitor of the GTPase dynamin that competitively blocks binding of dynamin to amphiphysin, preventing endocytosis. Reduces NMDA receptor internalization. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 1330.64 |
| 分子式 | C61H107N19O14 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 251634-22-7 |
| 序列号 | QVPSRPNRAP (Modifications: Gln-1 = Myr-Gln, Pro-10 = C-terminal amide) |
| 参考文献 | Nonget al (2003) Glycine binding primes NMDA receptor internalization. Nature 422 302. PMID: 12646920. Kittleret al (2000) Constitutive endocytosis of GABAA receptors by an association with the adaptin AP2 complex modulates inhibitory synaptic currents in hippocampal neurons. J.Neurosci. 20 7972. PMID: 11050117. Grabset al (1997) The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequence. J.Biol.Chem. 272 13419. PMID: 9148966. |