| 货号 | 3321/1 |
| 别名 | 2-(Propylthio)adenosine-5'-O-(β,γ-difl |
| 供应商 | Tocris |
| 生物活性 | Potent and selective P2Y12 receptor antagonist. Blocks ADP-induced inhibition of adenylyl cyclase in vitro(pKB =7.6) and inhibits ADP-induced aggregation of washed human platelets (pIC50 = 8.16). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >98 % |
| 计算分子量 | 703.26 |
| 分子式 | C14H18F2N5Na4O12P3S |
| 可溶性/溶解性 | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
| CAS号 | 145783-24-0 |
| 参考文献 | Simonet al (2001) Activity of adenosine diphosphates and triphosphates on a P2YT-type receptor in brain capillary endothelial cells. Br.J.Pharmacol. 132 173. PMID: 11156575. Ingallet al (1999) Antagonists of the platelet P receptor: a novel approach to antithrombotic therapy. J.Med.Chem. 42 213. PMID: 9925726. Humphrieset al (1994) FPL 66096: a novel, highly potent and selective antagonist at human platelet P2T-purinoceptors. Br.J.Pharmacol. 113 1057. PMID: 7858849. |