货号 | 1767/50 |
别名 | (2Z)-3-(4-Bromophenyl)-N,N-dimethyl |
供应商 | Tocris |
生物活性 | 5-HT re-uptake inhibitor; selective over noradrenalin and dopamine uptake (IC50 values are 0.33, 8.2 and 12 μM respectively). Modulates nociception and induces hyperglycemia in vivo, and is an orally active antidepressant. |
运输条件 | Blue Ice |
存放说明 | Ambient |
纯度 | >98 % |
计算分子量 | 390.15 |
分子式 | C16H17BrN2 2HCl |
可溶性/溶解性 | Soluble to 100 mM in water |
CAS号 | 56775-88-3 |
参考文献 | Sugimotoet al (1999) Involvement of serotonin in zimelidine-induced hyperglycemia in mice. Biol.Pharm.Bull. 22 1240. PMID: 10598036. Fasmeret al (1987) Changes in nociception after acute and chronic administration of zimelidine: different effects in the formalin test and substance P behavioural assay. Neuropharmacology 26 309. PMID: 2438584. Ogrenet al (1981) The pharmacology of zimelidine: a 5-HT selective reuptake inhibitor. Acta Psychiatr.Scand.Suppl. 290 127. PMID: 6452789. |