| 货号 | 3002/50 |
| 别名 | 2-(10-Hydroxydecyl)-5,6-dimethoxy-3 |
| 供应商 | Tocris |
| 生物活性 | Antioxidant and neuroprotective agent. Protects mitochondrial membranes against lipid peroxidation and blocks glutamate neurotoxicity in vitroandin vivo. Inhibits apoptosis of astrocytes via increased NGF production. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 338.44 |
| 分子式 | C19H30O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| CAS号 | 58186-27-9 |
| 参考文献 | Takumaet al (2000) CV-2619 protects cultured astrocytes against reperfusion injury via nerve growth factor production. Eur.J.Pharmacol. 406 333. PMID: 11040339. Civenniet al (1999) Inhibitory effect of the neuroprotective agent idebenone on arachidonic acid metabolism in astrocytes. Eur.J.Pharmacol. 370 161. PMID: 10323265. Zs-Nagy (1990) Chemistry, toxicology, pharmacology and pharmacokinetics of idebenone: a review. Arch.Gerontol.Geriatr. 11 177. PMID: 15374467. |