Dolasetron mesylate (50 MG)
货号：
5629/50 基本售价：
4689.5 元 规格：
50 mg
产品信息
概述| 货号 | 5629/50 |
| 别名 | 3-Oxooctahydro-2,6-methano-2H-quinolizin-8-yl 1H-indole-3-carboxylate methanesulfonate |
性能| 供应商 | Tocris |
| 生物活性 | Potent and selective 5-HT3 receptor antagonist (pIC50 = 7.55). Exhibits 200-fold selectivity for 5-HT3 over 5-HT1A, 5-HT1B and 5-HT2 receptors, and a range of other GPCRs. Blocks the 5-HT-elicited von Bezold-Jarisch reflex in rats and suppresses cisplatin-induced vomiting in ferrets. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 420.48 |
| 分子式 | C19H20N2O3 |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 100 mM in DMSO |
| 参考文献 | Miller (1993) Pharmacological properties of dolasetron, a potent and selective antagonist at 5-HT3 receptors. Drug Dev. Res. 2887. |
