| 货号 | 4005/50 |
| 别名 | N-(1,3-Benzodioxol-5-ylmethyl)-2,6- |
| 供应商 | Tocris |
| 生物活性 | Activator of aldehyde dehydrogenase 2 (ALDH2). Increases activity of wild-type ALDH2*1 and variant ALDH2*2 (by ~2-fold and 11-fold respectively). Capable of partly restoring mutant ALDH2*2 activity; protective against cardiac ischemia. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 324.16 |
| 分子式 | C15H11Cl2NO3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| 参考文献 | Berettaet al (2010) Characterization of the East Asian variant of aldehyde dehydrogenase-2. Bioactivation of nitroglycerin and effects of alda-1. J.Biol.Chem. 285 943. PMID: 19906643. Chenet al (2008) An activator of mutant and wildtype aldehyde dehydrogenase reduces ischemic damage to the heart. Science 321 1493. PMID: 18787169. |