| 货号 | 4148/50 |
| 别名 | (1S,4R)-4-[2-Amino-6-(cyclopropylam |
| 供应商 | Tocris |
| 生物活性 | Competitive reverse transcriptase inhibitor; inhibits HIV replication. Orally active and brain penetrant. Antiretroviral agent. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 335.37 |
| 分子式 | C14H18N6O.½H |
| 可溶性/溶解性 | Soluble to 100 mM in water and to 50 mM in DMSO |
| 参考文献 | Charneiraet al (2012) N-terminal valine adduct from the anti-HIV drug abacavir in rat haemoglobin as evidence for abacavir metabolism to a reactive aldehyde in vivo. Br.J.Pharmacol. 167 1353. PMID: 22725138. Harriganet al (2000) Resistance profile of the human immunodeficiency virus type 1 reverse transcriptase inhibitor abacavir (1592U89) after monotherapy and combination therapy. CNA2001 Investigative Group. J.Infect.Dis. 181 912. PMID: 10720512. Dalugeet al (1997) 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity. Antimicrob Agents Chemother. 41 1082. PMID: 9145874. |