Stattic (50 MG)
货号：
2798/50 基本售价：
4600.3 元 规格：
50 mg
产品信息
概述| 货号 | 2798/50 |
| 别名 | 6-Nitrobenzo[b]thiophene 1,1-dioxide |
性能| 供应商 | Tocris |
| 生物活性 | Small molecule inhibitor of STAT3. Inhibits binding of tyrosine-phosphorylated peptide motifs to STAT3 SH2 domain and inhibits STAT3 activation, dimerization and nuclear translocation. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >99 % |
| 计算分子量 | 211.19 |
| 分子式 | C8H5NO4S |
| 可溶性/溶解性 | Soluble to 50 mM in DMSO and to 5 mM in ethanol |
| CAS号 | 19983-44-9 |
| 参考文献 | Schustet al (2006) Stattic: a small-molecule inhibitor of STAT3 activation and dimerization. Chem.Biol. 13 1235. PMID: 17114005. |
