| 货号 | 2144/1 |
| 供应商 | Tocris |
| 生物活性 | Antagonist of 14.3.3 proteins (KD ≈80 nM). Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 2309.69 |
| 分子式 | C101H157N27O29S3 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 211364-78-2 |
| 序列号 | PHCVPRDLSWLDLEANMCLP |
| 参考文献 | Masterset al (2002) Survival-promoting functions of 14.3.3 proteins. Biochem.Soc.Transactions 30360. Masters and Fu (2001) 14.3.3 proteins mediate an essential anti-apoptotic signal. J.Biol.Chem. 276 45193. PMID: 11577088. Wanget al (1999) Isolation of high-affinity peptide antagonists of 14.3.3 proteins by phage display. Biochemistry 38 12499. PMID: 10493820. |