| 货号 | 1790/1 |
| 供应商 | Tocris |
| 生物活性 | Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the activator peptide. Once inside the cell, the disulfide bonds are subjected to reduction in the cytoplasm leading to release of the activator peptide. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 3198.81 |
| 分子式 | C144H225N43O34S3 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in water |
| 序列号 | KKWKMRRNQFWIKIQRC CSVEIWD* (Modifcations: Disulfide bridge between 17 -1*) |
| 参考文献 | Ron and Mochly-Rosen (1995) An autoregulatory region in protein kinase C: the pseudoanchoring site. Proc.Natl.Acad.Sci.U.S.A. 92 492. PMID: 7831317. Theodoreet al (1995) Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J.Neurosci. 15 7158. PMID: 7472470. Derossiet al (1994) The third helix of the antennapedia homeodomain translocates through biological membranes. J.Biol.Chem. 269 10444. PMID: 8144628. |