bpV(pic) (potassium hydrate)
货号：
14434-25mg 基本售价：
4590.0 元 规格：
25 mg
产品信息
概述| 货号 | 14434-25mg |
| 描述 | bpV(pic) is a bisperoxovanadium (bpV) compound that inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 31 nM).1 It also inhibits the vascular endothelial PTP, PTP-β (IC50 = 12.7 μM), and PTP-1βB (IC50 = 61 μM).1 bpV(pic) is also known to be an insulin mimetic capable of activating the insulin receptor kinase of cultured hepatoma cells, stimulating lipogenesis in adipocytes, and inhibiting the dephosphorylation of autophosphorylated insulin receptors and epidermal growth factor receptors of rat liver endosomes.2 |
| 别名 | Bisperoxovanadium(pic); |
性能| 供应商 | Cayman |
| 应用文献 |
1.Schmid, A.C.,Byrne, R.D.,Vilar, R., et al. Bisperoxovanadium compounds are potent PTEN inhibitors. FEBS Letters 566(1-3), 35-38 (2004).
2.Posner, B.I.,Faure, R.,Burgess, J.W., et al. Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics. The Journal of Biological Chemisty 269(6), 4596-4604 (1994).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥96% |
| 计算分子量 | 367.3 |
| 分子式 | C6H4NO7V • 2K [2H2O] |
| CAS号 | 148556-27-8 |
| 稳定性 | ≥ 2 years |
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