Imatinib Mesylate (CGP-57148B, STI-571)
货号:
1625-1000 基本售价:
4566.5 元 规格:
1g
产品信息
概述货号 | 1625-1000 |
描述 | An inhibitor of the bcr-abl tyrosine kinase. It acts by binding to the ATP binding site of bcr-abl. Imatinib also stimulates the entry of the bcr-abl tyrosine kinase into the nucleus, where it cannot perform its anti-apoptopic functions. It inhibits EOL-1 cell viability (IC₅₀ = 0.5 nM), phosphorylation of a fusion protein (IC₅₀ = 30 nM), and viability of BaF3 cells expressing Rhe-PDGFRα in the absence of IL-3 (IC₅₀ = 0.17 nM). |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20℃ |
外观 | White to off-white solid |