| 货号 | 19405-5mg |
| 描述 | Chaetoglobosin A is a mycotoxic cytochalasin that was first isolated from the marine-derived endophytic fungus C. globosum.1 It targets filamentous actin and demonstrates antibacterial and nematicidal effects as well as induces apoptosis in cancer cell lines.2,3,4 |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Cui, C.M.,Li, X.M.,Li, C.S., et al. Cytoglobosins A-G, cytochalasans from a marine-derived endophytic fungus, Chaetomium globosum QEN-14. Journal of Natural Products 73(4), 729-733 (2010). 2.Yahara, I.,Harada, F.,Sekita, S., et al. Correlation between effects of 24 different cytochalasins on cellular structures and cellular events and those on actin in vitro. Journal of Cell Biology 92, 69-78 (1982). 3.Hu, Y.,Zhang, W.,Zhang, P., et al. Nematicidal activity of chaetoglobosin A poduced by Chaetomium globosum NK102 against Meloidogyne incognita. Journal of Agricultural and Food Chemistry 61(1), 41-46 (2013). 4.Knudsen, P.B.,Hanna, B.,Ohl, S., et al. Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 28(6), 1289-1298 (2014). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 528.6 |
| 分子式 | C32H36N2O5 |
| CAS号 | 50335-03-0 |
| 稳定性 | ≥ 1 year |
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