6-trans Leukotriene B4
货号：
35250-100ug 基本售价：
4536.0 元 规格：
100 ug
产品信息
概述| 货号 | 35250-100ug |
| 描述 | 6-transLTB4 is produced by the non-enzymatic hydrolysis of LTA4.1 Oxidative decomposition of cysteinyl-leukotrienes such as LTC4 in the presence of myeloperoxidase and hypochlorous acid can also produce 6-transLTB4, but the physiologic importance of this mechanism is not clear.26-transLTB4 is relatively inactive compared to LTB4, but chemoattractant properties in neutrophils have been reported.3 |
| 别名 | 6-transLTB4;AlltransLTB4;5(S),12(R)-DiHETE; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Borgeat, P. and Samuelsson, B. Metabolism of arachidonic acid in polymorphonuclear leukocytes. J. Biol. Chem. 254, 7865-7869 (1979).
2.Lee, C.W.,Lewis, R.A.,Tauber, A.I., et al. The myeloperoxidase-dependent metabolism of leukotrienes C4, D4, and E4 to 6-trans-leukotriene B4 diastereoisomers and the subclass-specific S-diastereoisomeric sulfoxides. The Journal of Biological Chemisty 258, 15004-15010 (1983).
3.Fretland, D.J.,Widomski, D.L.,Anglin, C.P., et al. 6-trans-Leukotriene B4 is a neutrophil chemotoxin in the guinea pig dermis. Journal of Leukocyte Biology 49, 283-288 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥97% |
| 计算分子量 | 336.5 |
| 分子式 | C20H32O4 |
| CAS号 | 71652-82-9 |
| 稳定性 | ≥ 1 year |
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