MK-1775
货号：
2373-25 基本售价：
4505.0 元 规格：
25mg
产品信息
概述| 货号 | 2373-25 |
| 描述 | MK-1775 is a potent and selective inhibitor of the tyrosine kinase WEE1 (IC₅₀ = 5.2 nM). It selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20 ̊C |
| 外观 | Crystalline solid |
