L-DOPA methyl ester (hydrochloride)
货号：
16149-5g 基本售价：
4452.0 元 规格：
5 g
产品信息
概述| 货号 | 16149-5g |
| 描述 | L-DOPA (Item No. 13248) is a metabolic precursor of dopamine that is capable of crossing the blood brain barrier to act as a dopamine D1 receptor agonist. It is produced from L-tyrosine by trysosine hydroxylase. In the brain, L-DOPA is converted to dopamine by the enzyme aromatic L-amino acid decarboxylase. It is conventionally used to increase dopamine concentrations in the brain as a treatment for Parkinson’s disease and stroke recovery.1 L-DOPA methyl ester is a neutral derivative of L-DOPA formulated for increased solubility compared to the parent compound.2 |
| 别名 | 3,4-Dihydroxyphenylalanine methyl ester;LDME;Levodopa methyl ester;ST 41769; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Berends, H.I.,Nijlant, J.M.M.,Movig, K.L.L., et al. The clinical use of drugs influencing neurotransmitters in the brain to promote motor recovery after stroke; a Cochrane systematic review. European Journal of Physical and Rehabilitation Medicine 45(4), 621-630 (2009).
2.Kleedorfer, B.,Lees, A.J. and Stern, G.M. Subcutaneous and sublingual levodopa methyl ester in Parkinson’s disease. J.Neurol.Neurosurg.Psychiatry 54(4), 373 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 247.7 |
| 分子式 | C10H13NO4 • HCl |
| CAS号 | 1421-65-4 |
| 稳定性 | ≥ 2 years |
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