货号 | 2168/1 |
别名 | Benzyloxycarbonyl-Asp(OMe)-Gln-Met- |
供应商 | Tocris |
生物活性 | Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 685.72 |
分子式 | C29H40FN5O11S |
可溶性/溶解性 | Soluble to 13.71 mg/ml in DMSO |
序列号 | DQMD (Modifications: Asp-1 = Z-Asp(OMe), Asp-4 = (OMe)-fluoromethylketone) |
参考文献 | Banget al (2004) Differential response to MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents. Biochem.Pharmacol. 68 659. PMID: 15276073. Chouet al (2004) Alterations in protein kinase C activity and processing during zinc deficiency-induced cell death. Biochem.J. 383 63. PMID: 15198639. Izbanet al (2001) Characterization of NF-κB expression in Hodgkin's disease: inhibition of constitutively expressed NF-κB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells. Mod.Pathol. 14 297. PMID: 11301346. |