| 货号 | 2166/1 |
| 别名 | Benzyloxycarbonyl-Asp(OMe)-Glu(OMe) |
| 供应商 | Tocris |
| 生物活性 | Cell-permeable, irreversible inhibitor of caspase-3/CPP32; inhibits tumor cell apoptosis. Neuroprotective in rat hippocampus following seizures in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 668.67 |
| 分子式 | C30H41FN4O12 |
| 可溶性/溶解性 | Soluble to 13.37 mg/ml in DMSO |
| 序列号 | DEVD (Modifications: Asp-1 = Z-Asp(OMe), Glu-2 = Glu(OMe), Asp-4 = (OMe)-fluoromethylketone) |
| 参考文献 | Henshallet al (2000) Involvement of caspase-3-like protease in the mechanism of cell death following focally evoked limbic seizures. J.Neurochem. 74 1215. PMID: 10693954. Kugawaet al (2000) Apoptosis of NG108-15 cells induced by buprenorphine hydrochloride occurs via the caspase-3 pathway. Biol.Pharm.Bull. 23 930. PMID: 10963298. Brockstedet al (1998) Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. J.Biol.Chem. 273 28057. PMID: 9774422. |