| 货号 | 4195/10 |
| 别名 | 2-Amino-N-(3-octylphenyl)-3-(phosph |
| 供应商 | Tocris |
| 生物活性 | Sphingosine-1-phosphate receptor antagonist; inhibits S1P1 and S1P3 receptors (pKi values are 7.86 and 5.93 respectively). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 372.4 |
| 分子式 | C17H29N2O5 |
| 可溶性/溶解性 | Soluble to 10 mM in Acidified DMSO (5% 1N HCl in DMSO) with gentle warming and to 50 mM in 2eq. NaOH |
| 参考文献 | Aokiet al (2007) The suppressive effect of sphingosine-1-phosphate on monocyte-endothelium adhesion may be mediated by the rearrangement of the endothelial integrins α5β1 and αVβ3. J.Thromb.Haemost. 5 1292. PMID: 17403093. Mihovilovicet al (2007) High-fat/cholesterol diet promotes a S1P receptor-mediated antiapoptotic activity for VLDL. J.Lipid Res. 48 806. PMID: 17264352. Daviset al (2005) Sphingosine-1-phosphate analogs as receptor antagonists. J.Biol.Chem. 280 9833. PMID: 15590668. |