货号 | 2715/1 |
别名 | 3-(2-Oxo-2-phenylethyl)-uridine-5'-d |
供应商 | Tocris |
生物活性 | Potent and selective P2Y6 receptor agonist (EC50 values are 70, > 1000 and > 10000 nM for P2Y6, P2Y2 and P2Y4 receptors respectively). Induces contractions of rat isolated intrapulmonary arteries in vitro. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 566.26 |
分子式 | C17H18N2Na2O13P2 |
可溶性/溶解性 | Soluble in water (supplied pre-dissolved at a concentration of 10mM) |
CAS号 | 917567-60-3 |
参考文献 | Mitchellet al (2012) Identification of contractile P2Y1, P2Y6, and P2Y12 receptors in rat intrapulmonary artery using selective ligands. J.Pharmacol.Exp.Ther. 343 755. PMID: 22991416. El-Tayebet al (2006) Synthesis and structure-activity relationships of uracil nucleotide derivatives and analogues as agonists at human P2Y2, P2Y4 and P2Y6 receptors. J.Med.Chem. 49 7076. PMID: 17125260. |