货号 | 1947/500U |
供应商 | Tocris |
生物活性 | Antibacterial peptide. Stimulates angiogenesis and inhibits inflammatory responses by selectively blocking proteasome degradation of IκBα. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
计算分子量 | 4719.7 |
分子式 | C229H346N70O |
序列号 | RRRPRPPYLPRPRPPPFFPPRLPPRIPPGF (Modifications: Pro-39 = C-terminal amide) |
参考文献 | Gaczynskaet al (2003) Proline and arginine-rich peptides constitute a novel class of allosteric inhibitors of proteasome activity. Biochemistry 42 8663. PMID: 12873125. Gaoet al (2000) Inhibition of ubiquitin-proteasome pathway-mediated IκBα degradation by a naturally occuring antibacterial peptide. J.Clin.Invest. 106 439. PMID: 10930447. Liet al (2000) PR39, a peptide regulator of angiogenesis. Nat.Med. 6 356. PMID: 10613823. |