| 货号 | 3648/500U |
| 供应商 | Tocris |
| 生物活性 | Potent, endogenous neuromedin U receptor agonist (EC50 values are 65 and 91 pM at NMU1 and NMU2 respectively). Induces phase shifts in the circadian rhythm of locomotor activity following i.c.v. administration. Potent endogenous anorexigenic peptide. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 4241.97 |
| 分子式 | C193H307N57O |
| 可溶性/溶解性 | Soluble to 0.50 mg/ml in 20% acetonitrile / water |
| 序列号 | LPRLLHTDSRMATIDFPKKDPTTSLGRPFF (Modifications: Asn-36 = C-terminal amide) |
| 参考文献 | Mitchellet al (2009) Emerging pharmacology and physiology of neuromedin U and the structurally related peptide neuromedin S. Br.J.Pharmacol. 158 87. PMID: 19519756. Idaet al (2005) Neuromedin S is a novel anorexigenic hormone. Endocrinology 146 4217. PMID: 15976061. Moriet al (2005) Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 24 325. PMID: 15635449. |