| 货号 | 3266/1 |
| 别名 | Glucagon-like peptide 1 (9-36) amide |
| 供应商 | Tocris |
| 生物活性 | N-terminal truncated metabolite of glucagon-like peptide GLP-1-(7-36) (Cat. No. 2082) formed by dipeptidyl peptidase-IV cleavage. Acts as an antagonist at the human GLP-1 receptor. Inhibits hepatic glucose production in vivo and is a weak insulinotropic agent. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 3089.44 |
| 分子式 | C140H214N36O43 |
| 可溶性/溶解性 | Soluble to 2 mg/ml in 0.025% acetic acid |
| CAS号 | 161748-29-4 |
| 序列号 | EGTFTSDVSSYLEGQAAKEFIAWLVKGR (Modifications: Arg-28 = C-terminal amide) |
| 参考文献 | Elahiet al (2008) GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide is a glucoregulatory peptide. Obesity 16 1501. PMID: 18421270. Knudsen and Pridal (1996) Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur.J.Pharmacol. 318 429. PMID: 9016935. Deaconet al (1995) Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo. J.Clin.Endocrinol.Met. 80952. |