cis-Ned 19 (10 MG)
货号：
3953/10 基本售价：
4451.6 元 规格：
10 mg
产品信息
概述| 货号 | 3953/10 |
| 别名 | (1S,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid |
性能| 供应商 | Tocris |
| 生物活性 | Irreversible nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist; inhibits Ca2+ release (IC50 = 800 nM) and [32P]NAADP binding (IC50 = 15 μM). Stereoisomer of trans-Ned 19 (Cat. No. 3954). Fluorescently labels NAADP receptors in intact cells (excitation 351 and 365 nm using an ultraviolet Argon laser). |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >97 % |
| 计算分子量 | 514.59 |
| 分子式 | C30H31FN4O3< |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| 参考文献 | Nayloret al (2009) Identification of a chemical probe for NAADP by virtual screening. Nat.Chem.Biol. 5 220. PMID: 19234453. |
