S3QEL 2 (50 MG)
货号:
5735/50 基本售价:
4392.1 元 规格:
50 mg
产品信息
概述货号 | 5735/50 |
别名 | 1-(3,4-Dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
性能供应商 | Tocris |
生物活性 | Suppresses superoxide production by complex III in the mitochondria without affecting normal electron flux or cellular oxidative phosphorylation (IC50 = 1.7 μM). Suppresses HIF-1α accumulation and enhances survival and function of primary pancreatic islets in vitro. Cell permeable. |
运输条件 | Blue Ice |
存放说明 | -20℃ |
纯度 | >98 % |
计算分子量 | 323.44 |
分子式 | C19H25N5 |
可溶性/溶解性 | Soluble to 20 mM in DMSO with gentle warming and to 20 mM in ethanol with gentle warming |
参考文献 | Orret al (2015) Suppressors of superoxide production from mitochondrial complex III. Nat.Chem.Biol. 11 834. PMID: 26368590. |