| 货号 | 0917/50 |
| 别名 | 3α-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride |
| 供应商 | Tocris |
| 生物活性 | This cocaine analog binds with high affinity to the dopamine transporter (Ki = 30 nM) and blocks re-uptake of dopamine. However, it is a weak psychomotor stimulant and does not substitute for cocaine in addicted rats. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >99 % |
| 计算分子量 | 378.34 |
| 分子式 | C21H24CINO.HCl |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO |
| 参考文献 | Newmanet al (1995) Novel 4'-substituted and 4'4"-disubstituted 3α-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors. J.Med.Chem. 38 3933. PMID: 7562926. Newmanet al (1994) Novel 3α-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioural profiles. J.Med.Chem. 37 2258. PMID: 8057273. |