| 货号 | 14643-1g |
| 描述 | Lenalidomide is an analog of thalidomide (Item No. 14610) that, at 10 μM, alters gene expression and cell viability in a range of cancer cell lines.1 It also induces proliferation and enhances the functional capacity of T-lymphocytes, amplifying co-stimulatory signaling pathways.2 Lenalidomide is effective in hematologic cancers, including lymphomas and myelomas.3,4 |
| 别名 | Revlimid; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kim, K.,An, S.,Cha, H.J., et al. Lenalidomide induces apoptosis and alters gene expression in non-small cell lung cancer cells. Oncol.Lett. 5(2), 588-596 (2013). 2.McDaniel, J.M.,Pinilla-Ibarz, J. and Epling-Burnette, P.K. Molecular action of lenalidomide in lymphocytes and hematologic malignancies. Adv. Hematol. 513702 (2012). 3.Latif, T.,Chauhan, N.,Khan, R., et al. Thalidomide and its analogues in the treatment of multiple myeloma. Exp.Hermatol.Oncol. 1(1), 27 (2012). 4.Merli, M.,Ferrario, A.,Basilico, C., et al. Novel agents in indolent lymphomas. Ther.Adv.Hematol. 4(2), 133-148 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 259.3 |
| 分子式 | C13H13N3O3 |
| CAS号 | 191732-72-6 |
| 稳定性 | ≥ 2 years |
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