货号 | 2343-25 |
描述 | Inhibits the cullin-RING ubiquitin E3 ligase SCF-Skp2. Selectively inhibits Skp2-mediated p27 degradation by reducing p27 binding. In cancer cells, the compound induces p27 accumulation and promotes cell type-specific blocks in G1 or G2/M phases. |
供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | -20 ̊C |
外观 | Yellow solid |