JZL195
货号：
B1064-25 基本售价：
4320.5 元 规格：
25mg
产品信息
概述| 货号 | B1064-25 |
| 描述 | JZL195 is a potent dual inhibitor of Monoacylglycerol lipase (MAGL) (IC₅₀ = 2 nM) and fatty acid amide hydrolase (FAAH) (IC₅₀ = 4 nM), enzymes that degrade the endocannabinoids 2-arachidonoylglycerol (2-AG) and anandamide (AEA), the endogenous ligands for the cannabinoid G-protein coupled receptors CB1 and CB2. It poorly inhibits neuropathy target esterase and ABHD6 and does not inhibit other brain serine hydrolases. JZL 195 displays time-dependent inhibition of FAAH and MAGL in vivo, consistent with a covalent mechanism of activation. |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 外观 | White to off-white solid |
