8,9-DiHETE
货号：
10473-100ug 基本售价：
4228.0 元 规格：
100 ug
产品信息
概述| 货号 | 10473-100ug |
| 描述 | 8,9-DiHETE is a major metabolite of the 20:5 ω-3 fatty acid eicosapentaenoic acid (EPA; Item No. 90110).1 It is produced in rat liver microsomes, but not renal microsomes, by the generation of the unstable intermediate 8,9-epoxy eicosatetraenoic acid from EPA by cytochrome P450 monooxygenases.1 Dietary EPA supplementation in humans results in substantial urinary excretion of vicinal diols, including 8,9, 11,12, and 14,15 forms.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.VanRollins, M.,Frade, P.D., and Carretero, O.A. Oxidation of 5,8,11,14,17-eicosapentaenoic acid by hepatic and renal microsomes. Biochimica et Biophysica Acta 996, 133-149 (1988).
2.Knapp, H.R.,Miller, A.J., and Lawson, J.A. Urinary excretion of diols derived from eicosapentaenoic acid during N-3 fatty acid ingestion. Prostaglandins 42, 47-53 (1991).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 336.5 |
| 分子式 | C20H32O4 |
| CAS号 | 867350-87-6 |
| 稳定性 | ≥ 2 years |
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