SIRT2 Direct Fluorescent Screening Assay Kit
货号:
700280-96Well 基本售价:
4200.0 元 规格:
96 wells
产品信息
概述货号 | 700280-96Well |
描述 | The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. Cayman’s SIRT2 Direct Fluorescent Screening Assay provides a fluorescence-based method for screening SIRT2 inhibitors or activators. The procedure requires only two easy steps, both performed in the same microplate. In the first step, the substrate, which comprises the p53 sequence Gln-Pro-Lys-Lys(ε-acetyl)-AMC, is incubated with human recombinant SIRT2 along with its cosubstrate NAD+. Deacetylation sensitizes the substrate such that treatment with the Developer in the second step releases a fluorescent product. |
性能供应商 | Cayman |
运输条件 | Dry ice in continental US; may vary elsewhere |
存放说明 | -80 |
稳定性 | ≥ 1 year |
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