Staurosporine
货号:
1048-1 基本售价:
4200.0 元 规格:
1mg
产品信息
概述货号 | 1048-1 |
描述 | 2-Deoxy-D-Glucose is a glucose analog that has long been known to act as a competitive inhibitor of glucose metabolism. Upon transport into the cells, 2-DG is phosphorylated by hexokinase to 2-DG-P. However, unlike G-6-P, 2-DG-P cannot be further metabolized by phosphohexose isomerase, which converts G-6-P to fructose-6-phosphate . 2-Deoxyglucose-P is trapped and accumulated in the cells, leading to inhibition of glycolysis mainly at the step of phosphorylation of glucose by hexokinase. Inhibition of this rate-limiting step by 2-DG causes a depletion of cellular ATP, leading to blockage of cell cycle progression and cell death in vitro. |
性能供应商 | Biovision |
运输条件 | Blue Ice |
存放说明 | +4℃ |
外观 | White to off-white solid |