AGI-5198
货号：
2369-5 基本售价：
4197.5 元 规格：
5mg
产品信息
概述| 货号 | 2369-5 |
| 描述 | A potent, selective inhibitor of mutant IDH1 (isocitrate dehydrogenase 1). AGI-5198 inhibits IDH1 R132H and R132C mutants in vitro with IC₅₀ values of 0.07 and 0.16 µM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants (IC₅₀ s > 100 μM). Under conditions of near complete 2-HG (2-hydroxyglutarate) inhibition, AGI-5198 can induce demethylation of histone H3K9me3 and expression |
性能| 供应商 | Biovision |
| 运输条件 | Blue Ice |
| 存放说明 | -20 ̊C |
| 外观 | Crystalline solid |
