| 货号 | 2631/10 |
| 别名 | (2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(m |
| 供应商 | Tocris |
| 生物活性 | Broad spectrum inhibitor of MMPs (IC50 values are 3, 5, 6, 9 and 13 nM for MMP-9, MMP-1, MMP-2, MMP-14 and MMP-7 respectively). Inhibits peritoneal dissemination of human gastric cancer cells in vivo through inhibition of tumor angiogenesis. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 331.41 |
| 分子式 | C15H29N3O5 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 154039-60-8 |
| 参考文献 | Bjornlandet al (2005) Matrix metalloproteinases participate in osteosarcoma invasion. J.Surg.Res. 127 151. PMID: 16083752. Wadaet al (2003) Reduced angiogenesis in peritoneal dissemination of gastric cancer through gelatinase inhibition. Clin.Exp.Metastasis 20 431. PMID: 14524532. Rasmussen and McCann (1997) Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat. Pharmacol.Ther. 75 69. PMID: 9364582. |