| 货号 | 1980/10 |
| 别名 | N2-[[2-(2-Naphthalenyl)-1H-benz[g]i |
| 供应商 | Tocris |
| 生物活性 | Potent and selective somatostatin sst5 receptor agonist. Ki values are 0.4, 3.3, 52, 64 and 82 nM for cloned human sst5, sst1, sst2, sst3 and sst4 receptors respectively. Inhibits growth hormone release from rat pituitary cells (EC50 = 3.1 nM) and insulin release from mouse pancreatic islets (EC50 = 0.3 nM) in vitro. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 536.67 |
| 分子式 | C33H36N4O3 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 217480-27-8 |
| 参考文献 | Rohrer and Schaeffer (2000) Identification and characterization of subtype selective somatostatin receptor agonists. J.Physiol.Paris 94 211. PMID: 11087999. Strowskiet al (2000) Somatostatin inhibits insulin and glucagon secretion via two receptor subtypes: An in vitro study of pancreatic islets from somatostatin receptor 2 knockout mice. Endocrinology 141 111. PMID: 10614629. Rohreret al (1998) Rapid identification of subtype-selective agonists of the somatostatin receptor through combinatorial chemistry. Science 282 737. PMID: 9784130. |