| 货号 | 2961/10 |
| 别名 | (2R,3S)-N4-Hydroxy-N1-[(1S)-2-(meth |
| 供应商 | Tocris |
| 生物活性 | Potent, broad spectrum MMP inhibitor (IC50 values are 3, 4, 4, 6 and 20 nM for MMP -1, -2, -9, -7 and -3 respectively). Exhibits antiproliferative, anti-invasive and antimetastatic activity in human ovarian carcinoma xenografts in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >99 % |
| 计算分子量 | 477.64 |
| 分子式 | C23H31N3O4S2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO |
| CAS号 | 130370-60-4 |
| 参考文献 | Kohn and Liotta (1995) Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res. 55 1856. PMID: 7728753. Wanget al (1994) Matrix metalloproteinase inhibitor BB-94 (Batimastat) inhibits human colon tumor growth and spread in a patient-like orthotopic model in nude mice. Cancer Res. 54 4726. PMID: 8062271. Davieset al (1993) A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts. Cancer Res. 53 2087. PMID: 8347186. |