| 货号 | 4574/10 |
| 别名 | 4-[[4-(4-Hydroxyphenyl)-1-phthalazi |
| 供应商 | Tocris |
| 生物活性 | FAAH-like anandamide transporter (FLAT) inhibitor (IC50 = 1.8 μM); cytosolic variant of FAAH-1 that binds anandamide. Attenuates anandamide internalization and deactivation in vitroandin vivo respectively. Exhibits analgesic effects in rodent models of CB1-mediated nociceptive and inflammatory pain. |
| 运输条件 | Blue Ice |
| 存放说明 | Ambient |
| 纯度 | >98 % |
| 计算分子量 | 432.47 |
| 分子式 | C27H20N4O2 |
| 可溶性/溶解性 | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| 参考文献 | Piscitelli and Marzo (2012) "Redundancy" of endocannabinoid inactivation: new challenges and opportunities for pain control. ACS Chem.Neurosci. 3 356. PMID: 22860203. Fuet al (2011) A catalytically silent FAAH-1 variant drives anandamide transport in neurons. Nat.Neurosci. 15 64. PMID: 22101642. |