| 货号 | 11683-25mg |
| 描述 | Angelicin is a furanocoumarin typically isolated from the seeds of P. corylifolia. Like other furanocoumarins, angelicin has antibacterial activities against a number of Gram (+) and Gram (−) bacteria.1 It has also been shown to prevent tacrine-induced cytotoxicity in human liver-derived HepG2 cells (EC50 = 47 μg/ml) and vascular relaxation in phenylephrine-precontracted rat aorta.2,3 Angelicin also weakly inhibits topoisomerase II (IC50 = 404 μM).4 |
| 别名 | Bakuchicin;NSC 404563; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Khatune, N.A.,Islam, M.E.,Haque, M.E., et al. Antibacterial compounds from the seeds of Psoralea corylifolia. Fitoterapia 75, 228-230 (2004). 2.Cho, H.,Jun, J.Y.,Song, E.K., et al. Bakuchiol: A hepatoprotective compound of Psoralea corylifolia on tacrine-induced cytotoxicity in Hep G2 cells. Planta Medica 67, 750-751 (2001). 3.Li, X.,Lee, Y.J.,Kim, Y.C., et al. Bakuchicin induces vascular relaxation via endothelium-dependent NO-cGMP signaling. Phytotherapy Research 25, 1574-1578 (2011). 4.Sun, N.J.,Woo, S.H.,Cassady, J.M., et al. DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia. Journal of Natural Products 61, 362-366 (1998). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 186.2 |
| 分子式 | C11H6O3 |
| CAS号 | 523-50-2 |
| 稳定性 | ≥ 2 years |
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