| 货号 | 2540/100U |
| 别名 | N-(Piperidin-1-yl)-5-(4-(4-(3-(5-ca |
| 供应商 | Tocris |
| 生物活性 | Fluorescent form of AM 251 (Cat. No. 1117). AM 251 conjugated with 5-carboxytetramethylrhodamine (5-TAMRA) that fluoresces at 543 nm excitation (590 nm emission). Displays GPR55 binding activity. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 纯度 | >95 % |
| 计算分子量 | 974.97 |
| 分子式 | C56H53Cl2N7< |
| 可溶性/溶解性 | Soluble to 10 mM in DMSO |
| 参考文献 | Brunoet al (2014) Beyond radio-displacement techniques for identification of CB1 ligands: the first application of a fluorescence-quenching assay. Sci.Rep. 4 3757. PMID: 24441508. Sylantyevet al (2013) Cannabinoid- and lysophosphatidylinositol-sensitive receptor GPR55 boosts neurotransmitter release at central synapses. Proc.Natl.Acad.Sci.U.S.A. 110 5193. PMID: 23472002. Dalyet al (2010) Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries. Br.J.Pharmacol. 159 787. PMID: 20136833. Dalyet al (2008) Visualisation of vascular cannabinoid receptors and their potential interaction with α1-adrenergic receptors. Vascular and Smooth Muscle Phys.Soc. Symposium. |