| 货号 | 1464/1 |
| 供应商 | Tocris |
| 生物活性 | Peptide derived from the protease-activated receptor-1 (PAR1) that acts as a PAR1 selective agonist (EC50 = 1.9 μM). Stimulates PAR1-mediated plasma extravasation in vivo. Control Peptide RLLFT-NH2 (Cat. No. 3393) also available. |
| 运输条件 | Blue Ice |
| 存放说明 | -20℃ |
| 计算分子量 | 647.82 |
| 分子式 | C31H53N9O6 |
| 可溶性/溶解性 | Soluble to 1 mg/ml in water |
| CAS号 | 197794-83-5 |
| 序列号 | TFLLR (Modifications: Arg-5 = C-terminal amide) |
| 参考文献 | de Garavillaet al (2001) Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br.J.Pharmacol. 133 975. PMID: 11487506. Kawabataet al (2000) Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle. Life Sci. 67 2521. PMID: 11065174. Hollenberget al (1997) Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can.J.Physiol.Pharmacol. 75 832. PMID: 9315351. |