| 货号 | 2309/10 |
| 别名 | 2-[[[5-(2,6-Dimethoxyphenyl)-1-[4-[ |
| 供应商 | Tocris |
| 生物活性 | Potent non-peptide neurotensin (NT) receptor antagonist that binds with high affinity (IC50 = 0.32 - 3.96 nM; Ki < 10 nM). Attenuates amphetamine-induced hyperactivity and is orally active in vivo. |
| 运输条件 | Blue Ice |
| 存放说明 | 4℃ |
| 纯度 | >97 % |
| 计算分子量 | 685.86 |
| 分子式 | C39H51N5O6 |
| 可溶性/溶解性 | Soluble to 75 mM in DMSO and to 25 mM in water |
| CAS号 | 184162-64-9 |
| 参考文献 | Marie-Claireet al (2008) Effects of the selective neurotensin antagonist SR 142948A on 3,4-methylenedioxymethamphetamine-induced behaviours in mice. Neuropharmacology 54 1107. PMID: 18410947. Quereet al (1998) X-ray structural characterization of SR 142948, a novel potent synthetic neurotensin receptor antagonist. Bioorg.Med.Chem.Lett. 8 653. PMID: 9871577. Gullyet al (1997) Biochemical and pharmacological activities of SR 142948A, a new potent neurotensin receptor antagonist. J.Pharmacol.Exp.Ther. 280 802. PMID: 9023294. |